Beta-TCP (Digestive/Biliary Support)180 Tabs
Beta-TCP (Digestive/Biliary Support) from Biotics Research
(Save 10%. Use Coupon Code: Biotics10)
This product is gluten and dairy free!
Beta-TCP is support for normal cholesterol to bile acid conversion and healthy bile flow. Contains digestive and antioxidant enzymes, vitamin C, taurine and organic beet concentrate.
RECOMMENDATION: One (1) tablet with each meal as a dietary supplement or as otherwise directed by a healthcare professional.
Consider whenever the gallbladder has been removed or the need for supplemental bile salts is indicated. In the 16th century, Paracelsus introduced the concept of the tartaric diseases to explain how stones are formed in the human body by the precipitation of substances from body fluids, analogous to the deposition of tartar in wine casks.
Today we know that in industrialized countries more than 80% of gallstones consist mainly of cholesterol, the prevalence of gallstones is about 10%, and in people between 40 and 50 years of age the 5-year incidence is about 3%.
Bile, Defined Bile functions as the body’s “detergent” emulsification and absorption of lipids, critical for fat digestion and assimilation. Bile is produced by the liver, and is temporarily stored in the gall bladder. Bile is released into the small intestine in response to hormones, such as cholecystokinin, when fat enters the intestine.
Bile consists of a mixture of bile salts, bile acids, cholesterol, bilirubin and phospholipids. The ratio of individual lipids are critical to maintain a stable micellar concentration. The molar ratios are typically 5:15:80 for cholesterol/ phosphatidylcholine/bile salts. If the bile concentration becomes too high, cholesterol will precipitate and gallstones will form in the gall bladder, a condition known as cholelithiasis.
Bile Formation - Bile salts and acids represent oxidized derivatives of cholesterol. About 80% of the cholesterol in the body will eventually be disposed of as cholic acid. The primary bile acids, cholic acid and chenodeoxycholic acid, possess a carboxylic acid side chain which confers hydrophilic properties to the lipophilic sterol ring and creates detergent-like molecules.
The liver attaches taurine and glycine to bile acids to create bile salts (taurocholate or taurochenodeoxycholate and glycocholate or glycodeoxycholate, respectively). Bacterial enzymes in the colon can convert these to secondary bile acids, deoxycholate and lithocholate.
Bile and Digestion Bile is needed for efficient uptake of oily nutrients (fats). When bile acids and bile salts first encounter ingested fats, they act as emulsifiers to create suspensions which can be broken down enzymatically.
The process involves several important steps; sequentially indicated as:
1. The combined action of bile salts and pancreatic lipase initiates hydrolysis of triglycerides to free fatty acids and diglycerides, resulting in the formation of emulsions containing other lipid-soluble nutrients, including vitamins and carotenoids. The particle size of these emulsions ranges from 200 to 5,000 nm in diameter.
2. Lipase is then able to hydrolyze both di-and triglycerides to monoglycerides and free fatty acids. Lipase requires a smaller protein called colipase, another pancreatic product, to bind to triglycerides and activate the lipase.
3. Upon further release of bile salts, the lipid aggregates become smaller, from 3 to 10 nm in diameter. The normal endpoint of triglyceride digestion is a product containing 70% free fatty acid anions, 25% beta monoglycerides and 5% cholesterol. The micelles are then taken up by the epithelial cells of the brush border membrane via passive diffusion. After absorption, the fate of fatty acids depends upon their sizes. Medium chain fatty acids, with less than 10-12 carbons, pass directly from the mucosal cells into the portal blood and bind to serum albumin. Longer chain fatty acid anions are re-esterified with beta monoglycerides in the smooth endoplasmic reticulum to reform triglycerides. The newly synthesized triglycerides are complexed with apoproteins, cholesterol and phospholipids, to produce particles called chylomicrons. Chylomicrons are released from mucosal cells by exocytosis and enter the lymph, rather than entering the blood- stream directly.