Flax Seed Oil (Organic EFA Support) 100 Caps
Flax Seed Oil (Organic EFA Support) from Biotics Research Corp.
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Flax Seed Oil contains 1000 mg of certified organically grown, cold pressed flax seed oil per capsule. There is no CO2 extraction and the raw material is pressed in small batches to prevent the oil from being excessively heated. Flax seed oil should be used for increased or decreased blood fats, with immune insufficiency, and as a calcium synergist. With prostate hypertrophy it's an absolute necessity. Also use flax oil with skin conditions and cardiovascular support.
If there is a history of cancer you should take 3 grams of flax oil a day. Flax oil is very effective for benign and malignant cysts of the breast; especially for prevention. Dr. George Goodheart is absolutely correct when he indicates that raw, unprocessed oil is one of the major deficiencies in our country. Supplies pure flax seed oil, cold pressed, from certified organically grown flax seeds. Flax seed oil is a natural source of essential fatty acids.
Flax Seed Oil comes in 100 capsules per bottle. Biotics Flax Seed Oil is prepared from certified organically grown flax seed which is cold pressed to preserve maximum nutritional benefits.
Flax Seed Oil comes in 100 capsules per bottle. This oil is prepared from certified organically grown flax seed which is cold pressed to preserve maximum nutritional benefits. Flax Seed Oil comes in 100 capsules per bottle. It oil is prepared from certified organically grown flax seed which is cold pressed to preserve maximum nutritional benefits.
Supplemental Source of N-3 Fatty Acids Essential fatty acids fall into two broad classes, described as N-3 and N-6 fatty acids. These polyunsaturated fatty acids possess double bonds beginning at the third or fifth carbon atom from the methyl end of the carbon chain. Mammals cannot insert double bonds at these positions of fatty acids. Thus, N-3 and N-6 fatty acids cannot be synthesized from simple precursor fatty acids and they are considered dietary essentials. Alpha linolenic acid (18:3n- 3), ALA, is the parent compound of all long chain N-3 polyunsaturated fatty acids, including eicosapentaenoic acid (22:5n-3, EPA) and decosahexaenoic acid (22:6n-3 DHA).
ALA possesses 18 carbon atoms and 3 double bonds, hence the chemical name, 9,12,15, octadecatrienoic acid. Function of N-3 Fatty Acids Diets enriched in alpha linolenic acid, such as the Mediterranean diet, have been the subject of nutrition and medical research1 and beneficial effects note.2 Polyunsaturated fatty acids perform multiple functions. They are incorporated into membrane lipids to establish fluidity and membrane integrity.
As precursors of prostaglandins, thromboxanes and leukotrienes, polyunsaturates are essential to regulating most physiologic functions, including inflammation, platelet aggregation, pain and others. EPA and DHA possess protective effects on the cardiovascular system, and function as modulators based upon their conversion to eicosanoids.
In general, prostaglandins and thromboxanes synthesized from N-3 fatty acids, have a moderating influence on the body, and tend to return processes to equilibrium. For example, EPA leads to PGE3, a prostaglandin with 3 double bonds in its side chain. EPA is also converted to Thromboxane TX3. Both of these eicosanoids are believed to counterbalance the proinflammatory eicosanoids, such as PGE2 and Thromboxane TX4, formed from N-6 fatty acids.3, 8
For example, PGE3 and PGI3 prevent platelets from sticking and aggregating and they balance the parasympathetic nervous system. In contrast, PGE2 and Thromboxane TX4 from N-6 fatty acids increase the inflammatory response and respond to the sympathetic nervous system. Alpha linolenic acid has been found to support proper platelet function4 and normal serum cholesterol levels.5 Low levels of ALA in fat tissue are associated with decreased glucose tolerance.6 When elderly patients deficient in N-3 fatty acids were supplemented with pure ALA, lymphocytic response to mitogens improved.7 Mice fed a diet enriched in alpha linolenic acid increased the activity of cytotoxic T-cells.8
Flax seed oil may help balance joint health.9 N-3 fatty acids also play a role in the development and function of the brain and retina.10 N-3 fatty acids helps normalize immune functioning by inhibiting 5-lipoxygenase activity and reducing platelet-derived activity factor.11
N-3 Fatty Acids in the Diet Americans presently consume about 18% of the amount of N-3 fatty acids available in the diet a century ago.
It has been estimated that adults require 800 - 1,100 mg of ALA for health.12 However, no RDA has been established for N-3 essential fatty acids. The consumption of omega-3 fatty acids is relatively low in the typical Western diet compared to omega-6 fatty acids. N-6 and N-3 fatty acids compete for an enzyme involved in fatty acid elongation and desaturation, eicosanoid production and incorporation into membrane lipids. A key enzyme in this conversion is the rate-limiting step catalyzed by 6-desaturase. Excessive linoleic acid slows the desaturation of ALA.
Factors correlated with decreased delta 6-desaturation include diabetes; stress-related hormones; deficiencies of zinc and vitamin B6; excessive saturated fatty acids; trans fatty acids and cholesterol and possibly aging and high alcohol consumption.13 In vitro studies link viral infections, radiation and chemical carcinogens to 6-desaturase inhibition.14 In lab animals there is an age-related decline in delta 6- desaturase.15 Typical dietary sources of ALA are plant oils, especially flax-seed oil. DHA and EPA are most often concentrated in the fat of oily, cold water fish.
Flax seed as a Supplemental Source of N-3 Fatty Acids Flax seed oil represents one of the richest sources of ALA. Typically, flaxseed oil contains approximately 60% alpha ALA, and about 20% each of linoleic acid and oleic acid making up the difference. Recent research indicates that ALA can alter n-6/n-3 ratios16 and can be effectively converted to EPA in healthy humans17 although increased production of DHA was not observed.
1. Wallingford JC, Ph.D. and Yetley EA, Ph.D., R.D. Development of the Health Claims Regulations: The Case of Omega-3 Fatty Acids and Heart Disease. Nutrition Re- views 1991; 49 (11): 323. 2. Hartman IS, Ph.D. Alpha-Linolenic Acid: A Preventive in Secondary Coronary Events? Nutrition Reviews 1995; 53 (7): 194- 201. 3. Marshal LA and Johnston PV. Modulation of tissue prostaglandin synthesizing capacity by increased ratios of dietary alpha linolenic to linoleic acid. Lipids 1982; 905- 913. 4. Mest HJ et al. The influence of a linseed oil diet or fatty acid patterns in phospholipids and thromboxane formation in platelets in man. Klm Wchenschu 1983; 61: 187-191. 5. Garg ML; Wierzbicki AA; Thomson ABR and Clandinin MT. Lipids 1989; 24: 334-339. 6. Carlson LA et al. Association between a low adipose tissue content of polyunsaturated fatty acids and both glu- cose intolerance and hypertriglycerdemia in apparently healthy men. Acta Med Skand 1975; 197: 295-298. 7. Bjerve KS et al. Alpha linolenic acid deficiency in man: effect of ethyl linoleate on plasma and erythrocyte fatty acid composition and biosynthesis of prostaglandins. Am J Clin Nutr 1987; 46: 570-6.
8. Fritsche KL and Johnston PV. Modulation of Eicosanoid Production and Cell-mediated Cytotoxicity by Dietary à- Li- nolenic Acid in BALB/c Mice. Lipids 1989; 24 (4): 305-311. 9. Gemmell HA, DC and Jacobson BH. Effectiveness of Flaxseed Oil in the Symptomatic Treatment of Rheumatoid Arthritis: A Single Subject Experimental Design. Am J Chi- ropractic Med 1989; 2: 151-154. 10. Cook HW, Ph.D. Brain Metabolism of à-Linolenic Acid During Development. Nutrition 1991; 7 (6): 440. 11. Bourre JM, Bonneil M; Clement M; Dumont O; Durand G; Lafont H; Nalbone G and Piciotti M. Function of Di- etary Polyunsaturated Fatty Acids in the Nervous System. NEEDS JOURNAL CITATION. 12. Wu D; Meydani SN; Meydani M; Hayek MG; Huth P and Nicolosi RJ. Immunologic effects of marine- and plant- derived n-3 polyunsaturated fatty acids in nonhuman pri- mates. Am J Clin Nutr 1996; 63: 273- 280. 13. Galli C and Simopoulos AP. Dietary 3 and 6 Fatty Ac- ids Biological Effects and Nutritional Essentiality. Plenum Press 1989; 391-404. 14. Horrobin DF, A, Dphil, BM, Bch. The Importance of Gamma- Linolenic Acid and Prostaglandin E1 in Human Nutrition and Medicine. Journal of Holistic Medicine 1981; 3 (2): 118-139.
15. Hrelia S; Bordoni A; Celadon M; Turchetto E; Biagi PL and Rossi CA. Age-Related Changes in Linoleate and à- Linolenate Desaturation by Rat Liver Microsomes. Biochem and Biophy Res Comm 1989; 163 (1): 348-355. 16. Cunnane SC; Hamadeh MJ; Liede AC; Thompson LU; Wolever MS and Jenkins DJA. Am J Clin Nutr 1995; 61: 62- 68. Nutritional attributes of traditional flax seed in healthy young adults. 17. Mantzioris E; James MJ; Gibson RA and Cleland LG. Differences exist in the relationships between dietary lino- leic and à-linolenic acids and their respective long-chain metabolites. Am J Clin Nutr 1995; 61: 320-324.